Welcome

Welcome to European Macrophage and Dendritic Cell Society 2012 Meeting
September 1-3, 2012, Debrecen, Hungary 

The Annual Meeting of the European Macrophage and Dendritic Cell Society will take place in Debrecen this year. 


01st September (Saturday)

10.00 – 17.00 Registration & Poster Mounting

17.00 – 17.15 Opening & Welcome Address

17.15 – 18.00 INV01 Stephen Smale (Los Angeles)
Transcription in Immune Regulation

18.15 – Concert

19.00 – Welcome Reception

02nd September (Sunday)

PATTERN RECOGNITION RECEPTORS IN MACROPHAGES AND DENDRITIC CELLS

Session chair: Loems Ziegler-Heitbrock

9.00 – 9.30 INV02 Leonie Unterholzner (Dublin)
IFI16: an innate immune sensor for intracellular DNA

9.30 – 9.45 A01 Matthew J. Sweet (Brisbane)
Functional signifi cance of evolutionary divergence in Toll-like receptor-regulated gene expression in human versus mouse macrophages

9.45 – 10.15 INV03 Martin Schlee (Bonn)
Insights into RNA recognition by the innate immune receptor RIG-I

10.15 – 10.45 INV04 Thorsten Hagemann (London)
Tumour associated myeloid cells - mediators of cancer progression

10.45 – 11.15 Coffee & Posters

Session chair: Christian Bogdan

11.15 – 11.45 INV05 Francesca Granucci (Milan)
The multifaceted roles of CD14 in innate immune responses to LPS

11.45 – 12.00 A02 Cristina López-Rodriguez (Barcelona)
Gene expression induced by Toll-like receptors in macrophages requires the transcription factor NFAT5

12.00 – 12.30 INV06 Carsten Kirschning (Essen)
Erythromycin binding 23S rRNA segment activates TLR13

12.30 – 13.15 Lunch

TRANSCRIPTIONAL NETWORKS IN MACROPHAGES AND DENDRITIC CELLS

Session chair: Thomas Weichhart

13.15 – 13.45 INV07 Renato Ostuni (Milan)
The macrophage epigenome and the control of infl ammatory gene expression

13.45 – 14.00 B01 Marcello F. Stein (Erlangen)
Characterization of the human CD83 promoter reveals a complex NFkB/IRF-framework governing expression in mature dendritic cells

14.00 – 14.30 INV08 Grant D. Barish (Chicago)
The Bcl6 cistrome represses NF-kB-mediated infl ammation and attenuates atherosclerosis

14.30 – 14.45 B02 Anca V. Gafencu (Bucharest)
Macrophage-specifi c upregulation of apoE and apoCII genes by STAT1 acting on the multienhancer 2

Session chair: Zsuzsa Szondy

14.45 – 15.00 B03 Georg Stoecklin (Heidelberg)
Global analysis of mRNA translation during macrophage activation

15.00 – 15.30 INV09 Jan Tuckermann (Jena/Ulm)
New macrophage dependent and independent mechanisms of glucocorticoids to prevent endotoxin induced infl ammation

15.30 – 15.45 B04 Bence Dániel (Debrecen)
The global view on RXR regulated transcriptional events in mouse bone marrow derived macrophages

15.45 – 16.15 Coffee & Posters

ROLE OF MACROPHAGES IN PATHOPHYSIOLOGY

Session chair: Eva Rajnavolgyi

16.15 – 16.45 INV10 Bénédicte Chazaud (Paris)
AMPK regulates macrophage skewing during muscle tissue repair - implications on trophic activities of macrophages on muscle stem cells

16.45 – 17.15 INV11 Massimiliano Mazzone (Leuven)
Oxygen-sensing in macrophages: implications for cancer and ischemia

17.15 – 17.45 EMDS Biannual Prize Lecture
INV12 Antonio Castrillo (Madrid)

Regulation of homeostatic and infl ammatory macrophage functions by LXR Nuclear Receptors

18.30 – Buses leave from the Life Science Building

19.00 – Grill party

03rd September (Monday)

ROLE OF MACROPHAGES AND DENDRITIC CELLS IN TUMOR IMMUNOLOGY

Session chair: Maciej Siedlar

9.00 – 9.30 INV13 Sebastien Jaillon (Milan)
New approaches to target tumor-associated macrophages

9.30 – 9.45 D01 Numan Akram (Lyon)
Transcriptomic analysis of blood-derived macrophages identifi es 5-lipoxygenase activation protein as a key tumorinduced immune molecule in glioblastoma patients

9.45 – 10.00 D02 Elio Schouppe (Leuven)
MDSC subpopulations diff erentially aff ect distinct aspects of CD8+ T-cell activation

10.00 – 10.30 Coffee & Posters

ROLE OF MACROPHAGES AND DENDRITIC CELLS IN IMMUNOREGULATION

Session chair: Ulrike Schleicher

10.30 – 11.00 INV14 Vincenzo Bronte (Verona)
CCL2 orchestrates a tolerogenic environment in the spleen of tumor-bearing hosts

11.00 – 11.15 E01 Sampsa Matikainen (Helsinki)
(1,3)-s-glucans activate autophagy-dependent unconventional protein secretion from human macrophages

11.15 – 11.30 E02 Gerhard Krönke (Erlangen)
12/15-lipoxygenase orchestrates the clearance of apoptotic cells and maintains immunologic tolerance

11.30 – 11.45 E03 David A. Brown (Sydney)
A forebrain-immune cell pathway for the maintenance of CNS immune tolerance

11.45 – 12.45 EMDS Member General Assembly

12.45 – 13.30 Lunch

ROLE OF MACROPHAGES AND DENDRITIC CELLS IN INFL AMMATION

Session chair: Silvano Sozzani

13.30 – 14.00 INV15 Alan Stitt (Belfast)
Myeloid phenotype of endothelial progenitor cell sub-types – implications for infl ammatory responses during cell therapy

14.00 – 14.30 INV16 Walter Reith (Geneva)
Remodelling of DC function by rapid maturation-induced epigenetic silencing

14.30 – 14.45 F01 Dominik A. Rückerl (Edinburgh)
Identifi cation of helminth-induced microRNAs in macrophages reveals PI3K/Akt signalling as essential for IL-4-driven macrophage proliferation in vivo

MACROPHAGES, DENDRITIC CELLS AND MICROBES

Session chair: Guenter Weiss

14.45 – 15.00 G01 Geert Raes (Brussels)
Modulation of the complement system in peripheral blood monocytes contributes to tuberculosis-associated immune reconstitution infl ammatory syndrome

15.00 – 15.30 INV17 Duccio Cavalieri (Florence)
Systems biology of immune systems-microbiota interactions: turning complexity into simplicity

15.30 – 16.30 Poster Session

16.30 – Buses leave from the Life Science Building

17.30 – Puszta program & dinner (optional)

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